Spinal Muscular Atrophy

Also known as:
SMA
Spinal Muscular Atrophy

Last modified: 5th February 2023

Strong association with:
Rhabdomyolysis and hyperkalaemia

Implicated drugs:

Suxamethonium

Theoretical association with:
link
Paracetamol toxicity and acute liver failure
Feb. 5, 2023, 7:22 p.m.

Potentially implicated drugs:

Paracetamol

Overview

Spinal muscular atrophy (SMA) represents a spectrum of progressive neuromuscular disorders primarily associated with deletions or mutations in the survivor motor neuron genes

Rhabdomyolysis

Risk of inducing rhabdomyolysis and hyperkalaemia in the presence of lower motor neuron denervation hypersensitivity

Anesthesia and perioperative medical management of children with spinal muscular atrophy

Pediatric Anesthesia 2009