Exertional Heat Illness

Also known as:

EHI
Exertional Heat Illness

Last modified: 5th February 2023

Theoretical association with:

Malignant Hyperthermia

Feb. 5, 2023, 7:22 p.m.

Implicated drugs:

Desflurane

Enflurane

Halothane

Isoflurane

Methoxyflurane

Sevoflurane

Suxamethonium

EHI is a multisystem, life-threatening illness characterized by central nervous system (CNS) dysfunction (encephalopathy) and additional organ and tissue damage (eg, acute kidney injury, liver injury, rhabdomyolysis) in association with high body temperatures.

The relationship between exertional heat illness, exertional rhabdomyolysis, and malignant hyperthermia