Last modified: 5th February 2023
Implicated drugs:
Bupivacaine
Lignocaine
Prilocaine
Ropivacaine
Dravet syndrome (DS) is a severe form of epilepsy characterized by frequent, prolonged seizures often triggered by high body temperature (hyperthermia), developmental delay, speech impairment, ataxia, hypotonia, sleep disturbances, and other health problems.
Use of sodium channel blocking medications can aggravate seizures in Dravet syndrome
Pediatric Anesthesia 2022
https://onlinelibrary.wiley.com/doi/abs/10.1111/pan.14525