Dravet syndrome

Also known as:
Severe myoclonic epilepsy of infancy
SCN1A
Dravet syndrome

Last modified: 5th February 2023


Strong association with:
Seizures

Implicated drugs:

Bupivacaine

Lignocaine

Prilocaine

Ropivacaine

Overview

Dravet syndrome (DS) is a severe form of epilepsy characterized by frequent, prolonged seizures often triggered by high body temperature (hyperthermia), developmental delay, speech impairment, ataxia, hypotonia, sleep disturbances, and other health problems.

Use of sodium channel blocking medications can aggravate seizures in Dravet syndrome

Anesthetic considerations in Dravet Syndrome

Pediatric Anesthesia 2022

https://onlinelibrary.wiley.com/doi/abs/10.1111/pan.14525